Composition Engineering Opens an Avenue towards Efficient and Sustainable Nitrogen Fixation

Towards an ecological understanding of biological nitrogen fixation

N limitation to primary production and other ecosystem processes is widespread. To understand the causes and distribution of N limitation, we must understand the controls of biological N fixation. The physiology of this process is reasonably well characterized, but our understanding of ecological controls is sparse, except in a few cultivated ecosystems. We review information on the ecological ...

Immune checkpoint blockade opens an avenue of cancer immunotherapy with a potent clinical efficacy

Recent progress in tumor immunology has revealed that tumors generate immunologically restrained milieu during the process of their growth, which facilitates the escape of tumors from host immune systems. Immune checkpoint molecules, which transduce co-inhibitory signals to immuno-competent cells, are one of the most important components conferring the immunosuppressive capacity in the tumor mi...

Approaches towards nitrogen- and phosphorus-efficient rice

BACKGROUND AND AIMS Food production has to increase to meet the demand of a growing population. In light of the high energy costs and increasingly scarce resources, future agricultural systems have to be more productive and more efficient in terms of inputs such as fertilizer and water. The development of rice varieties with high yield under low-nutrient conditions has therefore become a breedi...

Toward Sustainable Nitrogen Fixation: Elucidating the Mechanism of Nitrogen Reduction by Molecular Catalysts

Towards a Sustainable Anti-Corruption Strategy: An Ethic-Induced Model

Literature abounds to show that the current anti-corruption strategies have failed to fight corruption because of neglect of ethics in these strategies, despite its importance. The purpose of this paper is to make a contribution to anti-corruption theory by developing a model that clarifies many complex ethical dilemmas around corruption. To develop a conceptual model, the extant literatures on...